3VAK
Structure of U2AF65 variant with BrU5 DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Splicing factor U2AF 65 kDa subunit | polymer | 174 | 19075.8 | 2 | UniProt (P26368) Pfam (PF00076) In PDB | Homo sapiens (human) | U2 auxiliary factor 65 kDa subunit, hU2AF(65), hU2AF65, U2 snRNP auxiliary factor large subunit |
2 | P, E | DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3') | polymer | 7 | 2065.1 | 2 | synthetic construct | ||
3 | A, B | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 5 | Chemie (DIO) | |||
4 | A, B | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
6 | B | N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE | non-polymer | 862.1 | 1 | Chemie (CPQ) | |||
7 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A, B: 148 - 237 (UniProt: P26368)
A, B: 258 - 336 (UniProt: P26368)
PDB | External Database | Details |
---|---|---|
Gly 143 | - | expression tag |
Pro 144 | - | expression tag |
Leu 145 | - | expression tag |
Gly 146 | - | expression tag |
Ser 147 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 42281.7 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 2343.4 | |
All* | Total formula weight | 44625.1 |