3VA1

Crystal structure of the mammalian MDC1 FHA domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mediator of DNA damage checkpoint protein 1	polymer	132	14589.7	2	UniProt (Q5PSV9) Pfam (PF00498)	Mus musculus (mouse)
2	C, D (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	E, F (A, B)	water	water		18.0	146	Chemie (HOH)

Sequence modifications

A, B: 29 - 139 (UniProt: Q5PSV9)

PDB	External Database	Details
Met 8	-	expression tag
Gly 9	-	expression tag
Ser 10	-	expression tag
Ser 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
Ser 18	-	expression tag
Ser 19	-	expression tag
Gly 20	-	expression tag
Leu 21	-	expression tag
Val 22	-	expression tag
Pro 23	-	expression tag
Arg 24	-	expression tag
Gly 25	-	expression tag
Ser 26	-	expression tag
His 27	-	expression tag
Met 28	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29179.4
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	29371.6

*Water molecules are not included.