3V8S
Human RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Rho-associated protein kinase 1 | polymer | 410 | 47485.7 | 4 | UniProt (Q13464) Pfam (PF00069) | Homo sapiens (human) | Renal carcinoma antigen NY-REN-35, Rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, ROCK-I, p160 ROCK-1, p160ROCK |
| 2 | E, F, G, H (A, B, C, D) | 1-(1H-indazol-5-yl)-3-(2-phenylethyl)urea | non-polymer | 280.3 | 4 | Chemie (0HD) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 872 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 189942.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1121.3 | |
| All* | Total formula weight | 191063.9 |
