3V7T

Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	TPSB2 protein	polymer	245	27491.4	4	UniProt (Q6NZY1) Pfam (PF00089) UniProt (by SIFTS) (P20231)	Homo sapiens (human)
2	E, G, I, J (A, B, C, D)	{(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone	non-polymer		495.4	4	Chemie (0GX)
3	F, H (A, B)	CARBONATE ION	non-polymer		60.0	2	Chemie (CO3)
4	K, L, M, N (A, B, C, D)	water	water		18.0	588	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	109965.7
Non-Polymers*	Number of molecules	6
	Total formula weight	2101.8
All*	Total formula weight	112067.5

*Water molecules are not included.