3V6C
Crystal Structure of USP2 in complex with mutated ubiquitin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ubiquitin carboxyl-terminal hydrolase 2 | polymer | 367 | 42171.7 | 1 | UniProt (O75604) Pfam (PF00443) In PDB | Homo sapiens (human) | 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin thiolesterase 2, Ubiquitin-specific-processing protease 2 |
2 | B | Ubiquitin | polymer | 91 | 10329.7 | 1 | UniProt (P0CG48) Pfam (PF00240) In PDB | Homo sapiens (human) | |
3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
6 | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A: 258 - 605 (UniProt: O75604)
B: -2 - 74 (UniProt: P0CG48)
PDB | External Database | Details |
---|---|---|
Met 239 | - | expression tag |
Gly 240 | - | expression tag |
Ser 241 | - | expression tag |
Ser 242 | - | expression tag |
His 243 | - | expression tag |
His 244 | - | expression tag |
His 245 | - | expression tag |
His 246 | - | expression tag |
His 247 | - | expression tag |
His 248 | - | expression tag |
Ser 249 | - | expression tag |
Ser 250 | - | expression tag |
Gly 251 | - | expression tag |
Leu 252 | - | expression tag |
Val 253 | - | expression tag |
Pro 254 | - | expression tag |
Arg 255 | - | expression tag |
Gly 256 | - | expression tag |
Ser 257 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -16 | - | expression tag |
Ala -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Leu -5 | - | expression tag |
Val -4 | - | expression tag |
Pro -3 | - | expression tag |
Ser 0 | Gly 76 | engineered mutation |
Asn 6 | Lys 82 | engineered mutation |
Thr 11 | Lys 87 | engineered mutation |
His 12 | Thr 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52501.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 228.4 | |
All* | Total formula weight | 52729.8 |