3V6B

VEGFR-2/VEGF-E complex structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	VEGF-E	polymer	137	15504.6	1	UniProt (Q2F842) Pfam (PF00341) UniProt (by SIFTS) (P52584)	Orf virus (ORFV)
2	B (R)	Vascular endothelial growth factor receptor 2	polymer	424	47694.2	1	UniProt (P35968) Pfam (PF21339) Pfam (PF00047) Pfam (PF07679) Pfam (PF22971)	Homo sapiens (human)	VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1

Sequence modifications

A: 11 - 123 (UniProt: Q2F842)

PDB	External Database	Details
Glu -13	-	expression tag
Leu -12	-	expression tag
Ser -11	-	expression tag
Thr -10	-	expression tag
Ser -9	-	expression tag
Leu -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Lys -5	-	expression tag
Ala -4	-	expression tag
Gly -3	-	expression tag
Phe -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
Glu 5	-	expression tag
Asn 6	-	expression tag
Leu 7	-	expression tag
Tyr 8	-	expression tag
Phe 9	-	expression tag
Gln 10	-	expression tag

R: 132 - 548 (UniProt: P35968)

PDB	External Database	Details
His 131	-	expression tag
Arg 547	Val 547	conflict
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63198.7
All*	Total formula weight	63198.7

*Water molecules are not included.