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3V6B

VEGFR-2/VEGF-E complex structure

Functional Information from GO Data
ChainGOidnamespacecontents
A0001666biological_processresponse to hypoxia
A0001934biological_processpositive regulation of protein phosphorylation
A0001938biological_processpositive regulation of endothelial cell proliferation
A0002040biological_processsprouting angiogenesis
A0005172molecular_functionvascular endothelial growth factor receptor binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0008083molecular_functiongrowth factor activity
A0016020cellular_componentmembrane
A0038084biological_processvascular endothelial growth factor signaling pathway
A0042056molecular_functionchemoattractant activity
A0045766biological_processpositive regulation of angiogenesis
A0048010biological_processvascular endothelial growth factor receptor signaling pathway
A0050918biological_processpositive chemotaxis
A0050930biological_processinduction of positive chemotaxis
A0051781biological_processpositive regulation of cell division
A0060754biological_processpositive regulation of mast cell chemotaxis
R0005021molecular_functionvascular endothelial growth factor receptor activity
R0005524molecular_functionATP binding
R0006468biological_processprotein phosphorylation
R0016020cellular_componentmembrane
R0019838molecular_functiongrowth factor binding
R0048010biological_processvascular endothelial growth factor receptor signaling pathway
Functional Information from PROSITE/UniProt
site_idPS00249
Number of Residues13
DetailsPDGF_1 Platelet-derived growth factor (PDGF) family signature. PPCVtlmRCGGCC
ChainResidueDetails
APRO49-CYS61

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255
ChainResidueDetails
AASN75

site_idSWS_FT_FI2
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
RASN158
RASN374
RASN395
RASN511
RASN523

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20145116, ECO:0000269|PubMed:21827946
ChainResidueDetails
RASN245
RASN318

221051

PDB entries from 2024-06-12

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