3V6B

VEGFR-2/VEGF-E complex structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001666	biological_process	response to hypoxia
A	0001938	biological_process	positive regulation of endothelial cell proliferation
A	0005172	molecular_function	vascular endothelial growth factor receptor binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0007165	biological_process	signal transduction
A	0008083	molecular_function	growth factor activity
A	0016020	cellular_component	membrane
A	0042056	molecular_function	chemoattractant activity
A	0050918	biological_process	positive chemotaxis
A	0050930	biological_process	induction of positive chemotaxis
A	0051781	biological_process	positive regulation of cell division
R	0005021	molecular_function	vascular endothelial growth factor receptor activity
R	0005524	molecular_function	ATP binding
R	0006468	biological_process	protein phosphorylation
R	0016020	cellular_component	membrane
R	0019838	molecular_function	growth factor binding
R	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00249
Number of Residues	13
Details	PDGF_1 Platelet-derived growth factor (PDGF) family signature. PPCVtlmRCGGCC

Chain	Residue	Details
A	PRO49-CYS61

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255

Chain	Residue	Details
A	ASN75

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site_id	SWS_FT_FI2
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
R	ASN158
R	ASN374
R	ASN395
R	ASN511
R	ASN523

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20145116, ECO:0000269|PubMed:21827946

Chain	Residue	Details
R	ASN245
R	ASN318

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