3V1R
Crystal structures of the reverse transcriptase-associated ribonuclease H domain of XMRV with inhibitor beta-thujaplicinol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Reverse transcriptase/ribonuclease H p80 | polymer | 180 | 19874.5 | 1 | UniProt (Q2F7J3) Pfam (PF00075) | Xenotropic MuLV-related virus VP35 (XMRV) | |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 4 | G, H (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | I (A) | 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one | non-polymer | 180.2 | 1 | Chemie (JTH) | |||
| 6 | J (A) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 497 - 671 (UniProt: Q2F7J3)
| PDB | External Database | Details |
|---|---|---|
| Asp 492 | - | expression tag |
| Arg 493 | - | expression tag |
| Trp 494 | - | expression tag |
| Gly 495 | - | expression tag |
| Ser 496 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19874.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 792.5 | |
| All* | Total formula weight | 20667.0 |
