3UZE
Crystal structure of the dengue virus serotype 3 envelope protein domain III in complex with the variable domains of Mab 4E11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Variable domains of murine anti-dengue Mab 4E11 | polymer | 253 | 27246.2 | 2 | Mus musculus (mouse) | ||
| 2 | C, D (C, D) | Envelope protein | polymer | 139 | 15084.9 | 2 | UniProt (Q7TGD1) Pfam (PF02832) UniProt (by SIFTS) (P27915) | Dengue virus 3 | |
| 3 | E, F, L, M, O (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | G, H, I, K, N (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | J (B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 6 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
C, D: 295 - 395 (UniProt: Q7TGD1)
| PDB | External Database | Details |
|---|---|---|
| Pro 396 | - | expression tag |
| Phe 397 | - | expression tag |
| Glu 398 | - | expression tag |
| Asp 399 | - | expression tag |
| Asp 400 | - | expression tag |
| Asp 401 | - | expression tag |
| Asp 402 | - | expression tag |
| Lys 403 | - | expression tag |
| Ala 404 | - | expression tag |
| Gly 405 | - | expression tag |
| Trp 406 | - | expression tag |
| Ser 407 | - | expression tag |
| His 408 | - | expression tag |
| Pro 409 | - | expression tag |
| Gln 410 | - | expression tag |
| Phe 411 | - | expression tag |
| Glu 412 | - | expression tag |
| Lys 413 | - | expression tag |
| Gly 414 | - | expression tag |
| Gly 415 | - | expression tag |
| Gly 416 | - | expression tag |
| Ser 417 | - | expression tag |
| Gly 418 | - | expression tag |
| Gly 419 | - | expression tag |
| Gly 420 | - | expression tag |
| Ser 421 | - | expression tag |
| Gly 422 | - | expression tag |
| Gly 423 | - | expression tag |
| Gly 424 | - | expression tag |
| Ser 425 | - | expression tag |
| Trp 426 | - | expression tag |
| Ser 427 | - | expression tag |
| His 428 | - | expression tag |
| Pro 429 | - | expression tag |
| Gln 430 | - | expression tag |
| Phe 431 | - | expression tag |
| Glu 432 | - | expression tag |
| Lys 433 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 84662.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1009.1 | |
| All* | Total formula weight | 85671.2 |
