3UZE

Crystal structure of the dengue virus serotype 3 envelope protein domain III in complex with the variable domains of Mab 4E11

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Variable domains of murine anti-dengue Mab 4E11	polymer	253	27246.2	2		Mus musculus (mouse)
2	C, D	Envelope protein	polymer	139	15084.9	2	UniProt (Q7TGD1) Pfam (PF02832) UniProt (by SIFTS) (P27915) In PDB	Dengue virus 3
3	A, B, C	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
4	A, B	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
5	B	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
6		water	water		18.0	277	Chemie (HOH)

Sequence modifications

C, D: 295 - 395 (UniProt: Q7TGD1)

PDB	External Database	Details
Pro 396	-	expression tag
Phe 397	-	expression tag
Glu 398	-	expression tag
Asp 399	-	expression tag
Asp 400	-	expression tag
Asp 401	-	expression tag
Asp 402	-	expression tag
Lys 403	-	expression tag
Ala 404	-	expression tag
Gly 405	-	expression tag
Trp 406	-	expression tag
Ser 407	-	expression tag
His 408	-	expression tag
Pro 409	-	expression tag
Gln 410	-	expression tag
Phe 411	-	expression tag
Glu 412	-	expression tag
Lys 413	-	expression tag
Gly 414	-	expression tag
Gly 415	-	expression tag
Gly 416	-	expression tag
Ser 417	-	expression tag
Gly 418	-	expression tag
Gly 419	-	expression tag
Gly 420	-	expression tag
Ser 421	-	expression tag
Gly 422	-	expression tag
Gly 423	-	expression tag
Gly 424	-	expression tag
Ser 425	-	expression tag
Trp 426	-	expression tag
Ser 427	-	expression tag
His 428	-	expression tag
Pro 429	-	expression tag
Gln 430	-	expression tag
Phe 431	-	expression tag
Glu 432	-	expression tag
Lys 433	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	84662.1
Non-Polymers*	Number of molecules	11
	Total formula weight	1009.1
All*	Total formula weight	85671.2

*Water molecules are not included.