3UYJ

Crystal structure of JMJD5 catalytic core domain in complex with nickle and alpha-KG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Lysine-specific demethylase 8	polymer	248	28683.6	2	UniProt (Q8N371) Pfam (PF13621) In PDB	Homo sapiens (human)	JMJC-containing demethylase, JmjC domain-containing protein 5, Jumonji domain-containing protein 5
2	A, B	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
3	A, B	2-OXOGLUTARIC ACID	non-polymer		146.1	2	Chemie (AKG)
4		water	water		18.0	209	Chemie (HOH)

Sequence modifications

A, B: 173 - 416 (UniProt: Q8N371)

PDB	External Database	Details
Gly 169	-	EXPRESSION TAG
Ser 170	-	EXPRESSION TAG
His 171	-	EXPRESSION TAG
Met 172	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57367.2
Non-Polymers*	Number of molecules	4
	Total formula weight	409.6
All*	Total formula weight	57776.8

*Water molecules are not included.