3UXJ
Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with NADP and PreQ0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NADPH-dependent 7-cyano-7-deazaguanine reductase | polymer | 290 | 33271.3 | 4 | UniProt (C3LTF1) Pfam (PF14819) Pfam (PF14489) UniProt (by SIFTS) (Q9KTK0) | Vibrio cholerae O1 biovar El Tor | 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase |
| 2 | E, I, O, S (A, B, C, D) | 7-DEAZA-7-AMINOMETHYL-GUANINE | non-polymer | 179.2 | 4 | Chemie (PRF) | |||
| 3 | F, R (A, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 4 | G, H, J, K, L... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 1112 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 287 (UniProt: C3LTF1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Leu 262 | Arg 262 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 133085.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2762.1 | |
| All* | Total formula weight | 135847.3 |
