3UW9
Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K8acK12ac)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 4 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (human) | Protein HUNK1 |
| 2 | E, F | histone 4 peptide (H4K8acK12ac) | polymer | 11 | 1114.3 | 2 | UniProt (P62805) In PDB | Homo sapiens | peptide (H4K8acK12ac) |
| 3 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 42 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | Thr 43 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 62626.1 | |
| All* | Total formula weight | 62626.1 |
