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3UVO

Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1B

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WD repeat-containing protein 5polymer31834794.41UniProt (P61964)
Pfam (PF00400)
Homo sapiens (human)WDR5, BMP2-induced 3-kb gene protein
2B
(B)
Histone-lysine N-methyltransferase SETD1Bpolymer111204.31UniProt (Q9UPS6)Homo sapiensLysine N-methyltransferase 2G, SET domain-containing protein 1B, hSET1B
3C, D
(A, B)
waterwater18.098Chemie (HOH)
Sequence modifications
A: 21 - 334 (UniProt: P61964)
PDBExternal DatabaseDetails
Gly 17-expression tag
Ala 18-expression tag
Met 19-expression tag
Gly 20-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35998.8
All*Total formula weight35998.8
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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