3UVN
Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | WD repeat-containing protein 5 | polymer | 318 | 34794.4 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | WDR5, BMP2-induced 3-kb gene protein |
| 2 | B, D (B, D) | Histone-lysine N-methyltransferase SETD1A | polymer | 11 | 1200.3 | 2 | UniProt (O15047) | Homo sapiens | Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1 |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A, C: 21 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Ala 18 | - | expression tag |
| Met 19 | - | expression tag |
| Gly 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71989.5 | |
| All* | Total formula weight | 71989.5 |
