3UVC

MMP12 in a complex with the dimeric adduct: 5-(5-phenylhydantoin)-5-phenylhydantoin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Macrophage metalloelastase	polymer	164	18280.5	2	UniProt (P39900) Pfam (PF00413) In PDB	Homo sapiens (human)	MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12
2	A, B	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	A, B	CALCIUM ION	non-polymer		40.1	7	Chemie (CA)
4	B, A	IMIDAZOLE	non-polymer		69.1	5	Chemie (IMD)
5	B, A	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
6	A	(4R,4'S)-4,4'-diphenyl-4,4'-biimidazolidine-2,2',5,5'-tetrone	non-polymer		350.3	1	Chemie (0D2)
7	B, A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
8		water	water		18.0	490	Chemie (HOH)

Sequence modifications

A, B: 106 - 263 (UniProt: P39900)

PDB	External Database	Details
Met 105	-	expression tag
Ala 219	Glu 219	engineered mutation
His 264	-	expression tag
His 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36560.9
Non-Polymers*	Number of molecules	27
	Total formula weight	1705.6
All*	Total formula weight	38266.5

*Water molecules are not included.