3UVC
MMP12 in a complex with the dimeric adduct: 5-(5-phenylhydantoin)-5-phenylhydantoin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Macrophage metalloelastase | polymer | 164 | 18280.5 | 2 | UniProt (P39900) Pfam (PF00413) | Homo sapiens (human) | MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12 |
| 2 | C, D, H, T, U... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | E, F, G, K, V... (A, B) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) | |||
| 4 | BA, I, J, O, Z (B, A) | IMIDAZOLE | non-polymer | 69.1 | 5 | Chemie (IMD) | |||
| 5 | AA, L, M, N, R... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 6 | P (A) | (4R,4'S)-4,4'-diphenyl-4,4'-biimidazolidine-2,2',5,5'-tetrone | non-polymer | 350.3 | 1 | Chemie (0D2) | |||
| 7 | CA, Q (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 8 | DA, EA (A, B) | water | water | 18.0 | 490 | Chemie (HOH) |
Sequence modifications
A, B: 106 - 263 (UniProt: P39900)
| PDB | External Database | Details |
|---|---|---|
| Met 105 | - | expression tag |
| Ala 219 | Glu 219 | engineered mutation |
| His 264 | - | expression tag |
| His 265 | - | expression tag |
| His 266 | - | expression tag |
| His 267 | - | expression tag |
| His 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36560.9 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 1705.6 | |
| All* | Total formula weight | 38266.5 |
