Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | 0D2314 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 302 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 303 |
| Chain | Residue |
| A | GLU199 |
| A | GLU201 |
| A | HOH414 |
| A | HOH431 |
| A | ASP124 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 304 |
| Chain | Residue |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| A | HOH402 |
| A | HOH444 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 305 |
| Chain | Residue |
| A | ASP175 |
| A | GLY176 |
| A | GLY178 |
| A | ILE180 |
| A | ASP198 |
| A | GLU201 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 306 |
| Chain | Residue |
| A | HIS172 |
| A | IMD307 |
| B | HIS228 |
| B | CL301 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD A 307 |
| Chain | Residue |
| A | HIS172 |
| A | ZN306 |
| A | 0D2314 |
| A | HOH464 |
| B | HIS228 |
| B | PRO238 |
| B | CL301 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IMD A 312 |
| Chain | Residue |
| A | GLY169 |
| A | ASP170 |
| A | PHE171 |
| A | IMD313 |
| A | HOH418 |
| B | HIS172 |
| B | ZN308 |
| B | IMD309 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 308 |
| Chain | Residue |
| A | SER142 |
| A | THR145 |
| A | HOH401 |
| A | HOH410 |
| A | HOH427 |
| A | HOH428 |
| A | HOH446 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 309 |
| Chain | Residue |
| A | ASN120 |
| A | TYR121 |
| A | ARG127 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 310 |
| Chain | Residue |
| A | HOH609 |
| B | LYS151 |
| B | ASN153 |
| B | HOH557 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 311 |
| Chain | Residue |
| A | ARG135 |
| A | SER150 |
| A | LYS151 |
| B | ASN153 |
| B | THR154 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE IMD A 313 |
| Chain | Residue |
| A | GLY169 |
| A | IMD312 |
| A | HOH469 |
| A | HOH660 |
| A | HOH667 |
| B | HIS172 |
| B | ZN308 |
| B | IMD309 |
| B | HOH446 |
| site_id | BC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 0D2 A 314 |
| Chain | Residue |
| A | GLY179 |
| A | ILE180 |
| A | LEU181 |
| A | ALA182 |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | PRO238 |
| A | TYR240 |
| A | ZN301 |
| A | IMD307 |
| A | HOH413 |
| A | HOH435 |
| A | HOH498 |
| B | SER229 |
| B | SER230 |
| B | PRO238 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 315 |
| Chain | Residue |
| A | LEU214 |
| A | THR239 |
| A | TYR240 |
| A | LYS241 |
| A | HOH425 |
| A | HOH572 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 301 |
| Chain | Residue |
| A | HIS172 |
| A | ZN306 |
| A | IMD307 |
| B | HIS228 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| B | ASN120 |
| B | TYR121 |
| B | ARG127 |
| B | HOH616 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 303 |
| Chain | Residue |
| B | HIS218 |
| B | HIS222 |
| B | HIS228 |
| B | IMD311 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 304 |
| Chain | Residue |
| B | HIS168 |
| B | ASP170 |
| B | HIS183 |
| B | HIS196 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 305 |
| Chain | Residue |
| B | ASP124 |
| B | GLU199 |
| B | GLU201 |
| B | HOH417 |
| B | HOH423 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 306 |
| Chain | Residue |
| B | ASP158 |
| B | GLY190 |
| B | GLY192 |
| B | ASP194 |
| B | HOH408 |
| B | HOH412 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 307 |
| Chain | Residue |
| B | ASP175 |
| B | GLY176 |
| B | GLY178 |
| B | ILE180 |
| B | ASP198 |
| B | GLU201 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 308 |
| Chain | Residue |
| A | IMD312 |
| A | IMD313 |
| A | HOH469 |
| B | HIS172 |
| B | IMD309 |
| B | HOH446 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IMD B 309 |
| Chain | Residue |
| A | IMD312 |
| A | IMD313 |
| B | ASP170 |
| B | HIS172 |
| B | PHE185 |
| B | ILE191 |
| B | ZN308 |
| B | HOH446 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 310 |
| Chain | Residue |
| B | ARG110 |
| B | HOH463 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD B 311 |
| Chain | Residue |
| B | ALA182 |
| B | HIS218 |
| B | HIS222 |
| B | HIS228 |
| B | ZN303 |
| B | EDO312 |
| B | HOH442 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 312 |
| Chain | Residue |
| B | HIS218 |
| B | PRO238 |
| B | TYR240 |
| B | IMD311 |
| B | HOH407 |
| B | HOH581 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ALA219 | |
| B | ALA219 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP124 | |
| A | GLY190 | |
| A | GLY192 | |
| A | ASP194 | |
| A | HIS196 | |
| A | ASP198 | |
| A | GLU199 | |
| A | GLU201 | |
| A | HIS218 | |
| A | HIS222 | |
| A | HIS228 | |
| A | ASP158 | |
| B | ASP124 | |
| B | ASP158 | |
| B | HIS168 | |
| B | ASP170 | |
| B | ASP175 | |
| B | GLY176 | |
| B | GLY178 | |
| B | ILE180 | |
| B | HIS183 | |
| B | GLY190 | |
| A | HIS168 | |
| B | GLY192 | |
| B | ASP194 | |
| B | HIS196 | |
| B | ASP198 | |
| B | GLU199 | |
| B | GLU201 | |
| B | HIS218 | |
| B | HIS222 | |
| B | HIS228 | |
| A | ASP170 | |
| A | ASP175 | |
| A | GLY176 | |
| A | GLY178 | |
| A | ILE180 | |
| A | HIS183 | |
