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3UU6

The GLIC pentameric Ligand-Gated Ion Channel Loop2-22' mutant reduced in solution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, EGlr4197 proteinpolymer32136525.95UniProt (Q7NDN8)
Pfam (PF02931)
In PDB
Gloeobacter violaceusGLIC, ligand-gated ion channel
2A, B, C, D, EDIUNDECYL PHOSPHATIDYL CHOLINEnon-polymer622.810Chemie (PLC)
3A, B, C, D, ECHLORIDE IONnon-polymer35.55Chemie (CL)
4E, A, B, C, DDODECYL-BETA-D-MALTOSIDEnon-polymer510.66Chemie (LMT)
5ASODIUM IONnon-polymer23.01Chemie (NA)
6waterwater18.074Chemie (HOH)
Sequence modifications
A, B, C, D, E: 2 - 317 (UniProt: Q7NDN8)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
Ala -1-expression tag
Ala 0-expression tag
Ala 1-expression tag
Ser 27Cys 69engineered mutation
Cys 33Lys 75engineered mutation
Cys 246Leu 288engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight182629.6
Non-Polymers*Number of molecules22
Total formula weight9492.3
All*Total formula weight192121.9
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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