3UOH
Aurora A in complex with RPM1722
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aurora kinase A | polymer | 279 | 32359.1 | 2 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (human) | Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A |
| 2 | C, G (A, B) | 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | non-polymer | 385.2 | 2 | Chemie (0C4) | |||
| 3 | D, E, F, H, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | J, K (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 123 - 401 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Asp 287 | Thr 287 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64718.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1080.8 | |
| All* | Total formula weight | 65799.0 |
