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3UMH

X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with cadmium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAmyloid beta A4 proteinpolymer21125062.41UniProt (P05067)
Pfam (PF12925)
In PDB
Homo sapiens (human)
2AACETATE IONnon-polymer59.02Chemie (ACT)
3ACADMIUM IONnon-polymer112.49Chemie (CD)
4waterwater18.095Chemie (HOH)
Sequence modifications
A: 295 - 500 (UniProt: P05067)
PDBExternal DatabaseDetails
Met 294-initiating methionine
Ile 501-expression tag
Glu 502-expression tag
Gly 503-expression tag
Arg 504-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight25062.4
Non-Polymers*Number of molecules11
Total formula weight1129.8
All*Total formula weight26192.2
*Water molecules are not included.

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PDB entries from 2024-03-27

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