3UM8
Wild-type Plasmodium falciparum DHFR-TS complexed with cycloguanil and NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 608 | 71828.0 | 2 | UniProt (A7UD81) Pfam (PF00186) Pfam (PF00303) In PDB | Plasmodium falciparum | DHFR-TS |
| 2 | A, B | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | non-polymer | 251.7 | 2 | Chemie (1CY) | |||
| 3 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 4 | A | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | water | water | 18.0 | 456 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 143656.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2184.2 | |
| All* | Total formula weight | 145840.2 |
