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3UM2

Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, D)
BRO1 domain-containing protein BROXpolymer37642533.42UniProt (Q5VW32)
Pfam (PF03097)
Homo sapiens (human)BRO1 domain- and CAAX motif-containing protein
2B, D
(B, E)
Charged multivesicular body protein 5polymer202130.42UniProt (Q9NZZ3)Homo sapiensChromatin-modifying protein 5, SNF7 domain-containing protein 2, Vacuolar protein sorting-associated protein 60, Vps60, hVps60
3E, F, G
(A, D)
GLYCEROLnon-polymer92.13Chemie (GOL)
4H, I, J, K
(A, B, D, E)
waterwater18.0183Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight89327.6
Non-Polymers*Number of molecules3
Total formula weight276.3
All*Total formula weight89603.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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