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3UM2

Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP5

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005635cellular_componentnuclear envelope
A0007084biological_processmitotic nuclear membrane reassembly
A0016020cellular_componentmembrane
A0031965cellular_componentnuclear membrane
A0070062cellular_componentextracellular exosome
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005635cellular_componentnuclear envelope
D0007084biological_processmitotic nuclear membrane reassembly
D0016020cellular_componentmembrane
D0031965cellular_componentnuclear membrane
D0070062cellular_componentextracellular exosome
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL A 1
ChainResidue
ATYR86
AGLN105
AARG272
AGLU276
AGLU338
AALA339
AHOH449

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 378
ChainResidue
AHOH391
AILE166
ATYR214

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL D 378
ChainResidue
DILE330
DTYR331
DPHE332
DHOH442

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS283
DLYS283

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PDB entries from 2025-06-18

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