3UIN

Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SUMO-conjugating enzyme UBC9	polymer	158	18030.8	1	UniProt (P63279) Pfam (PF00179)	Homo sapiens (human)	SUMO-protein ligase, Ubiquitin carrier protein 9, Ubiquitin carrier protein I, Ubiquitin-conjugating enzyme E2 I, Ubiquitin-protein ligase I, p18
2	B (B)	Small ubiquitin-related modifier 2	polymer	80	9177.3	1	UniProt (P61956) Pfam (PF11976)	Homo sapiens (human)	SUMO-2, HSMT3, SMT3 homolog 2, SUMO-3, Sentrin-2, Ubiquitin-like protein SMT3A, Smt3A
3	C (C)	Ran GTPase-activating protein 1	polymer	171	18572.5	1	UniProt (P46060) Pfam (PF07834)	Homo sapiens (human)	RanGAP1
4	D (D)	E3 SUMO-protein ligase RanBP2	polymer	69	7926.8	1	UniProt (P49792) Pfam (PF12185)	Homo sapiens (human)	358 kDa nucleoporin, Nuclear pore complex protein Nup358, Nucleoporin Nup358, Ran-binding protein 2, RanBP2, p270
5	E, F, G, H (A, B, C, D)	water	water		18.0	42	Chemie (HOH)

Sequence modifications

B: 14 - 93 (UniProt: P61956)

PDB	External Database	Details
Met 55	Val 55	SEE REMARK 999

C: 419 - 587 (UniProt: P46060)

PDB	External Database	Details
Ser 417	-	expression tag
Leu 418	-	expression tag

D: 2629 - 2695 (UniProt: P49792)

PDB	External Database	Details
Ser 2627	-	expression tag
Leu 2628	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53707.4
All*	Total formula weight	53707.4

*Water molecules are not included.