3UIC
Crystal Structure of FabI, an Enoyl Reductase from F. tularensis, in complex with a Novel and Potent Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 280 | 30006.6 | 16 | UniProt (Q5NGQ3) Pfam (PF13561) In PDB | Francisella tularensis subsp. tularensis | |
2 | F, G, H, I, J... | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 16 | Chemie (NAD) | |||
3 | F, G, H, I, J... | 1-(3,4-dichlorobenzyl)-5,6-dimethyl-1H-benzimidazole | non-polymer | 305.2 | 16 | Chemie (09T) | |||
4 | water | water | 18.0 | 861 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 1 - 260 (UniProt: Q5NGQ3)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 16 |
Total formula weight | 480105.0 | |
Non-Polymers* | Number of molecules | 32 |
Total formula weight | 15498.0 | |
All* | Total formula weight | 495603.0 |