3UEN
Crystal structure of TopBP1 BRCT4/5 domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA topoisomerase 2-binding protein 1 | polymer | 203 | 22238.4 | 1 | UniProt (Q92547) Pfam (PF00533) | Homo sapiens (human) | DNA topoisomerase II-beta-binding protein 1, TopBP1, DNA topoisomerase II-binding protein 1 |
| 2 | B (A) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 3 | C, D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | H (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 549 - 746 (UniProt: Q92547)
| PDB | External Database | Details |
|---|---|---|
| Gly 544 | - | expression tag |
| Pro 545 | - | expression tag |
| Leu 546 | - | expression tag |
| Gly 547 | - | expression tag |
| Ser 548 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22238.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 518.6 | |
| All* | Total formula weight | 22756.9 |






