3UEH
Crystal structure of human Survivin H80A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Baculoviral IAP repeat-containing protein 5 | polymer | 146 | 16759.1 | 2 | UniProt (O15392) Pfam (PF00653) | Homo sapiens (human) | Apoptosis inhibitor 4, Apoptosis inhibitor survivin |
| 2 | C, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | E, G (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | F (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 142 (UniProt: O15392)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Ala 80 | His 80 | engineered mutation |
| Lys 129 | Glu 129 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33518.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 555.3 | |
| All* | Total formula weight | 34073.4 |
