3UDL

3-heterocyclyl quinolone bound to HCV NS5B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	HCV NS5B polymerase	polymer	576	64103.5	4	UniProt (Q99AU2) Pfam (PF00998) UniProt (by SIFTS) (P26663) In PDB	Hepatitis C virus subtype 1b
2	A, B, C, D	3-(5-benzyl-1,2,4-oxadiazol-3-yl)-6-fluoro-1-[2-fluoro-4-(trifluoromethyl)benzyl]-7-(4-methylpiperazin-1-yl)quinolin-4(1H)-one	non-polymer		595.6	4	Chemie (KLI)
3		water	water		18.0	964	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 570 (UniProt: Q99AU2)

PDB	External Database	Details
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
His -2	-	EXPRESSION TAG
His -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	256413.9
Non-Polymers*	Number of molecules	4
	Total formula weight	2382.2
All*	Total formula weight	258796.1

*Water molecules are not included.