3UAN
Crystal structure of 3-O-sulfotransferase (3-OST-1) with bound PAP and heptasaccharide substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Heparan sulfate glucosamine 3-O-sulfotransferase 1 | polymer | 269 | 31403.9 | 2 | UniProt (O35310) Pfam (PF00685) In PDB | Mus musculus (mouse) | Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1, Heparan sulfate 3-O-sulfotransferase 1 |
| 2 | C | 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid | branched | 1552.3 | 1 | In PDB GlyTouCan (G04206TC) | |||
| 3 | D | 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 1376.1 | 1 | In PDB GlyTouCan (G46176LD) | |||
| 4 | A, B | ADENOSINE-3'-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (A3P) | |||
| 5 | B | beta-D-glucopyranuronic acid | non-polymer | 194.1 | 1 | Chemie (BDP) | |||
| 6 | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A, B: 48 - 311 (UniProt: O35310)
| PDB | External Database | Details |
|---|---|---|
| Gly 43 | - | expression tag |
| Ser 44 | - | expression tag |
| Pro 45 | - | expression tag |
| Asn 46 | - | expression tag |
| Ser 47 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62807.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2928.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1048.5 | |
| All* | Total formula weight | 66784.7 |
