3UA4

Crystal Structure of Protein Arginine Methyltransferase PRMT5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein arginine N-methyltransferase 5	polymer	745	84747.7	2	UniProt (P46580) Pfam (PF17285) Pfam (PF05185) Pfam (PF17286)	Caenorhabditis elegans
2	C (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	D, E (A, B)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, B: 1 - 734 (UniProt: P46580)

PDB	External Database	Details
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Leu 735	-	expression tag
Glu 736	-	expression tag
His 737	-	expression tag
His 738	-	expression tag
His 739	-	expression tag
His 740	-	expression tag
His 741	-	expression tag
His 742	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	169495.4
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	169587.5

*Water molecules are not included.