3U8I
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Phospholipase A2, membrane associated | polymer | 124 | 14141.0 | 2 | UniProt (P14555) Pfam (PF00068) In PDB | Homo sapiens (human) | GIIC sPLA2, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2, NPS-PLA2, Phosphatidylcholine 2-acylhydrolase 2A |
| 2 | A, B | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | A, B | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28282.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 394.1 | |
| All* | Total formula weight | 28676.1 |
