3U8H
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Phospholipase A2, membrane associated | polymer | 124 | 13945.0 | 2 | UniProt (P14555) Pfam (PF00068) In PDB | Homo sapiens (human) | GIIC sPLA2, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2, NPS-PLA2, Phosphatidylcholine 2-acylhydrolase 2A |
2 | A, B | (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID | non-polymer | 487.6 | 2 | Chemie (BHP) | |||
3 | A, B | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
5 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27890.0 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1277.4 | |
All* | Total formula weight | 29167.4 |