3U7X

Crystal structure of the human eIF4E-4EBP1 peptide complex without cap

Replaces:  3SMU

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Eukaryotic translation initiation factor 4E	polymer	217	25130.2	2	UniProt (P06730) Pfam (PF01652) In PDB	Homo sapiens (human)	eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
2	C, D	Eukaryotic translation initiation factor 4E-binding protein 1	polymer	20	2357.8	2	UniProt (Q13541) In PDB	Homo sapiens	4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I
3	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	B, A	UNKNOWN ATOM OR ION	non-polymer			20	Chemie (UNX)
5		water	water		18.0	123	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	54976.0
Non-Polymers*	Number of molecules	24
	Total formula weight	384.3
All*	Total formula weight	55360.2

*Water molecules are not included.