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3U7X

Crystal structure of the human eIF4E-4EBP1 peptide complex without cap

Replaces:  3SMU
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Eukaryotic translation initiation factor 4Epolymer21725130.22UniProt (P06730)
Pfam (PF01652)
Homo sapiens (human)eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
2C, D
(C, D)
Eukaryotic translation initiation factor 4E-binding protein 1polymer202357.82UniProt (Q13541)Homo sapiens4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I
3E, O, P, Q
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
4AA, BA, F, G, H...
(B, A)
UNKNOWN ATOM OR IONnon-polymer20Chemie (UNX)
5CA, DA, EA, FA
(A, B, C, D)
waterwater18.0123Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight54976.0
Non-Polymers*Number of molecules24
Total formula weight384.3
All*Total formula weight55360.2
*Water molecules are not included.

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PDB entries from 2025-07-09

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