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3U4W

Src in complex with DNA-templated macrocyclic inhibitor MC4b

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proto-oncogene tyrosine-protein kinase Srcpolymer27531557.31UniProt (P00523)
Pfam (PF07714)
Gallus gallus (chicken)c-Src kinase, Proto-oncogene c-Src, pp60c-src, p60-Src
2B
(B)
macrocyclic inhibitor MC4Bpolymer5736.81BIRD (PRD_001022)
3C, I, J
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
4D, E, F, G, H
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
5K, L
(A, B)
waterwater18.0325Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32294.1
Non-Polymers*Number of molecules8
Total formula weight756.6
All*Total formula weight33050.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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