3U2O
Dihydroorotate Dehydrogenase (DHODH) crystal structure in complex with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 395 | 42929.2 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase, Dihydroorotate oxidase |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D (A) | methyl 4-{[(2Z)-2-cyano-3-hydroxypent-2-enoyl]amino}-4'-fluorobiphenyl-2-carboxylate | non-polymer | 368.4 | 1 | Chemie (03U) | |||
| 5 | E, F, G (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | H, I (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | J (A) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42929.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1350.1 | |
| All* | Total formula weight | 44279.3 |
