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3U2O

Dihydroorotate Dehydrogenase (DHODH) crystal structure in complex with small molecule inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADihydroorotate dehydrogenase (quinone), mitochondrialpolymer39542929.21UniProt (Q02127)
Pfam (PF01180)
In PDB
Homo sapiens (human)DHOdehase, Dihydroorotate oxidase
2AFLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3AOROTIC ACIDnon-polymer156.11Chemie (ORO)
4Amethyl 4-{[(2Z)-2-cyano-3-hydroxypent-2-enoyl]amino}-4'-fluorobiphenyl-2-carboxylatenon-polymer368.41Chemie (03U)
5AACETATE IONnon-polymer59.03Chemie (ACT)
6ASULFATE IONnon-polymer96.12Chemie (SO4)
7waterwater18.0256Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42929.2
Non-Polymers*Number of molecules8
Total formula weight1350.1
All*Total formula weight44279.3
*Water molecules are not included.

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PDB entries from 2024-03-27

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