3U15
Structure of hDMX with Dimer Inducing Indolyl Hydantoin RO-2443
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Protein Mdm4 | polymer | 100 | 11187.0 | 4 | UniProt (O15151) In PDB | Homo sapiens (human) | Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4 |
2 | A, B, C, D | (5Z)-5-[(6-chloro-7-methyl-1H-indol-3-yl)methylidene]-3-(3,4-difluorobenzyl)imidazolidine-2,4-dione | non-polymer | 401.8 | 4 | Chemie (03M) | |||
3 | A, D | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 14 - 111 (UniProt: O15151)
PDB | External Database | Details |
---|---|---|
Gly 12 | - | expression tag |
Pro 13 | - | expression tag |
Ser 17 | Cys 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 44747.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1799.3 | |
All* | Total formula weight | 46547.2 |