3U11
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | polymer | 210 | 24626.1 | 2 | UniProt (Q9Y3Q4) Pfam (PF00027) In PDB | Homo sapiens (human) | |
2 | A, B | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
4 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B: 521 - 723 (UniProt: Q9Y3Q4)
PDB | External Database | Details |
---|---|---|
Gln 514 | - | expression tag |
Gly 515 | - | expression tag |
Pro 516 | - | expression tag |
Ser 517 | - | expression tag |
Ser 518 | - | expression tag |
Pro 519 | - | expression tag |
Met 520 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49252.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1118.9 | |
All* | Total formula weight | 50371.1 |