3TY0
Structure of PPARgamma ligand binding domain in complex with (R)-5-(3-((3-(6-methoxybenzo[d]isoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)phenyl)-5-methyloxazolidine-2,4-dione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 277 | 31593.6 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | C, D (A, B) | (5R)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione | non-polymer | 484.5 | 2 | Chemie (082) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A, B: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 201 | - | expression tag |
| Ser 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63187.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 968.9 | |
| All* | Total formula weight | 64156.2 |
