3TXO
PKC eta kinase in complex with a naphthyridine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein kinase C eta type | polymer | 353 | 40493.1 | 1 | UniProt (P24723) Pfam (PF00069) Pfam (PF00433) In PDB | Homo sapiens (human) | PKC-L, nPKC-eta |
| 2 | A | 2-methyl-N~1~-[3-(pyridin-4-yl)-2,6-naphthyridin-1-yl]propane-1,2-diamine | non-polymer | 293.4 | 1 | Chemie (07U) | |||
| 3 | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 333 - 683 (UniProt: P24723)
| PDB | External Database | Details |
|---|---|---|
| Gly 331 | - | EXPRESSION TAG |
| Pro 332 | - | EXPRESSION TAG |
| Glu 675 | Ser 675 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40493.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 293.4 | |
| All* | Total formula weight | 40786.5 |
