3TWJ
Rho-associated protein kinase 1 (ROCK 1) IN COMPLEX WITH RKI1447
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Rho-associated protein kinase 1 | polymer | 410 | 47485.7 | 4 | UniProt (Q13464) Pfam (PF00069) | Homo sapiens (human) | Renal carcinoma antigen NY-REN-35, Rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, ROCK-I, p160 ROCK-1, p160ROCK |
| 2 | E, H (A, C) | 1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea | non-polymer | 326.4 | 2 | Chemie (07R) | |||
| 3 | F, G, I (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 189942.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 839.0 | |
| All* | Total formula weight | 190781.6 |
