3TW6
Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate carboxylase protein | polymer | 1165 | 127532.0 | 4 | UniProt (Q2K340) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) Pfam (PF00682) Pfam (PF02436) Pfam (PF00364) | Rhizobium etli | |
| 2 | AA, E, F, L, M... (D, A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 3 | BA, G, N, U (D, A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 4 | CA, H, O, V (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | DA, EA, I, J, P... (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) | |||
| 6 | K, Y (A, C) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 7 | Q (B) | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL | non-polymer | 228.3 | 1 | Chemie (BTI) | |||
| 8 | X (C) | PHOSPHONOACETIC ACID | non-polymer | 140.0 | 1 | Chemie (PAE) | |||
| 9 | FA, GA, HA, IA (A, B, C, D) | water | water | 18.0 | 793 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 1154 (UniProt: Q2K340)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Ala 882 | Thr 882 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 510128.0 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 4327.6 | |
| All* | Total formula weight | 514455.6 |
