Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004736 | molecular_function | pyruvate carboxylase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006090 | biological_process | pyruvate metabolic process |
A | 0006094 | biological_process | gluconeogenesis |
A | 0016874 | molecular_function | ligase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0003824 | molecular_function | catalytic activity |
B | 0004736 | molecular_function | pyruvate carboxylase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0006090 | biological_process | pyruvate metabolic process |
B | 0006094 | biological_process | gluconeogenesis |
B | 0016874 | molecular_function | ligase activity |
B | 0046872 | molecular_function | metal ion binding |
C | 0003824 | molecular_function | catalytic activity |
C | 0004736 | molecular_function | pyruvate carboxylase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0006090 | biological_process | pyruvate metabolic process |
C | 0006094 | biological_process | gluconeogenesis |
C | 0016874 | molecular_function | ligase activity |
C | 0046872 | molecular_function | metal ion binding |
D | 0003824 | molecular_function | catalytic activity |
D | 0004736 | molecular_function | pyruvate carboxylase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0006090 | biological_process | pyruvate metabolic process |
D | 0006094 | biological_process | gluconeogenesis |
D | 0016874 | molecular_function | ligase activity |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 1600 |
Chain | Residue |
A | GLY63 |
A | PRO64 |
A | ILE65 |
A | GLU66 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 1601 |
Chain | Residue |
A | TYR987 |
A | LYS989 |
A | VAL990 |
site_id | AC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE ADP A 2000 |
Chain | Residue |
A | VAL211 |
A | HIS216 |
A | GLN240 |
A | ASN243 |
A | LEU285 |
A | GLU297 |
A | MG2002 |
A | LYS209 |
A | LEU210 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 2001 |
Chain | Residue |
A | ASP549 |
A | KCX718 |
A | HIS747 |
A | HIS749 |
A | HOH1251 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG A 2002 |
Chain | Residue |
A | GLU283 |
A | GLU297 |
A | ADP2000 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 2005 |
Chain | Residue |
A | MET534 |
A | ARG535 |
A | GLU537 |
A | ASP768 |
A | HOH1182 |
A | HOH1245 |
site_id | AC7 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE COA A 4011 |
Chain | Residue |
A | ARG429 |
A | ARG469 |
A | GLN470 |
A | ASP471 |
A | ARG472 |
A | THR1031 |
A | LEU1032 |
A | ASN1055 |
B | ARG43 |
B | PHE44 |
B | HOH1343 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 1600 |
Chain | Residue |
B | GLY63 |
B | ILE65 |
B | GLU66 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 1601 |
Chain | Residue |
B | TYR987 |
B | LYS989 |
B | VAL990 |
site_id | BC1 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE ADP B 2000 |
Chain | Residue |
B | LYS124 |
B | LYS166 |
B | GLY171 |
B | GLY173 |
B | ARG174 |
B | MET176 |
B | GLU208 |
B | LYS209 |
B | LEU210 |
B | VAL211 |
B | HIS216 |
B | GLN240 |
B | ASN243 |
B | GLU283 |
B | LEU285 |
B | GLU297 |
B | THR454 |
B | HOH1222 |
B | HOH1223 |
B | MG2002 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN B 2001 |
Chain | Residue |
B | ASP549 |
B | KCX718 |
B | HIS747 |
B | HIS749 |
B | HOH1376 |
site_id | BC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG B 2002 |
Chain | Residue |
B | GLU283 |
B | GLU297 |
B | HOH1228 |
B | ADP2000 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE BTI B 2003 |
Chain | Residue |
B | ARG353 |
B | THR355 |
B | ASP399 |
B | ASN434 |
B | LYS1119 |
B | HOH1235 |
site_id | BC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG B 2005 |
Chain | Residue |
B | MET534 |
B | ARG535 |
B | GLU537 |
B | ASP768 |
B | HOH1348 |
B | HOH1349 |
site_id | BC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL C 1600 |
Chain | Residue |
C | GLY63 |
C | PRO64 |
C | ILE65 |
C | GLU66 |
site_id | BC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL C 1601 |
Chain | Residue |
C | TYR987 |
C | LYS989 |
C | VAL990 |
site_id | BC8 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE ADP C 2000 |
Chain | Residue |
C | LEU210 |
C | VAL211 |
C | HIS216 |
C | GLN240 |
C | GLU283 |
C | GLU297 |
C | THR454 |
C | HOH1302 |
C | MG2002 |
C | PAE2003 |
C | LYS166 |
C | MET176 |
C | GLU208 |
C | LYS209 |
site_id | BC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN C 2001 |
Chain | Residue |
C | ASP549 |
C | KCX718 |
C | HIS747 |
C | HIS749 |
C | HOH1160 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG C 2002 |
Chain | Residue |
C | GLU283 |
C | GLU297 |
C | HOH1302 |
C | ADP2000 |
C | PAE2003 |
site_id | CC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PAE C 2003 |
Chain | Residue |
C | LYS245 |
C | GLU283 |
C | GLU297 |
C | ASN299 |
C | ARG301 |
C | GLN303 |
C | VAL304 |
C | GLU305 |
C | HOH1302 |
C | HOH1304 |
C | ADP2000 |
C | MG2002 |
site_id | CC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE COA C 4011 |
Chain | Residue |
C | ARG427 |
C | ARG429 |
C | LYS468 |
C | ARG469 |
C | GLN470 |
C | ASP471 |
C | ARG472 |
C | ALA473 |
C | ILE1026 |
C | THR1031 |
C | LEU1032 |
D | PHE44 |
D | HOH1263 |
D | HOH1329 |
site_id | CC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL D 1600 |
Chain | Residue |
D | GLY63 |
D | PRO64 |
D | ILE65 |
D | GLU66 |
site_id | CC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL D 1601 |
Chain | Residue |
D | TYR987 |
D | LYS989 |
D | VAL990 |
site_id | CC6 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE ADP D 2000 |
Chain | Residue |
D | LYS166 |
D | MET176 |
D | LYS209 |
D | LEU210 |
D | VAL211 |
D | HIS216 |
D | GLN240 |
D | ASN243 |
D | GLU283 |
D | LEU285 |
D | GLU297 |
D | THR454 |
D | MG2002 |
site_id | CC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN D 2001 |
Chain | Residue |
D | ASP549 |
D | KCX718 |
D | HIS747 |
D | HIS749 |
D | HOH1340 |
site_id | CC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG D 2002 |
Chain | Residue |
D | GLU283 |
D | GLU297 |
D | ADP2000 |
site_id | CC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG D 2005 |
Chain | Residue |
D | MET534 |
D | ARG535 |
D | GLU537 |
D | ASP768 |
D | HOH1156 |
D | HOH1353 |
Functional Information from PROSITE/UniProt
site_id | PS00188 |
Number of Residues | 18 |
Details | BIOTIN Biotin-requiring enzymes attachment site. GDvLvsIeAMKMetaIhA |
Chain | Residue | Details |
A | GLY1109-ALA1126 | |
site_id | PS00866 |
Number of Residues | 15 |
Details | CPSASE_1 Carbamoyl-phosphate synthase subdomain signature 1. YPVMLKASwggGGrG |
Chain | Residue | Details |
A | TYR161-GLY175 | |
site_id | PS00867 |
Number of Residues | 8 |
Details | CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. FIEVNPRI |
Chain | Residue | Details |
A | PHE295-ILE302 | |