3TVM
Structure of the mouse CD1d-SMC124-iNKT TCR complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Antigen-presenting glycoprotein CD1d1 | polymer | 285 | 32632.7 | 2 | UniProt (P11609) Pfam (PF16497) Pfam (PF07654) | Mus musculus (mouse) | T cell surface glycoprotein CD1d |
| 2 | B, F (B, F) | beta-2-microglobulin | polymer | 99 | 11660.4 | 2 | UniProt (P01887) Pfam (PF07654) | Mus musculus (mouse) | |
| 3 | C, G (C, G) | Valpha14 (mouse variable domain, human constant domain) | polymer | 209 | 23055.6 | 2 | Pfam (PF09291) UniProt (by SIFTS) (P01848) | Mus musculus Homo sapiens | |
| 4 | D, H (D, H) | Vbeta8.2 (mouse variable domain, human constant domain) | polymer | 241 | 27027.0 | 2 | Pfam (PF07654) UniProt (by SIFTS) (A0A5B9) | Mus musculus Homo sapiens | |
| 5 | I, K (I, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | J, L (J, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 7 | M, P (A, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | N, Q (A, E) | N-[(2S,3R)-10-[(1R,2R)-2-decylcyclopropyl]-1-(alpha-D-galactopyranosyloxy)-3-hydroxydecan-2-yl]hexacosanamide | non-polymer | 910.4 | 2 | Chemie (07P) | |||
| 9 | O (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 10 | R (E) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 11 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, E: 1 - 279 (UniProt: P11609)
B, F: 1 - 99 (UniProt: P01887)
| PDB | External Database | Details |
|---|---|---|
| His 201 | Asp 219 | variant |
| His 280 | - | expression tag |
| His 281 | - | expression tag |
| His 282 | - | expression tag |
| His 283 | - | expression tag |
| His 284 | - | expression tag |
| His 285 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 85 | Asp 105 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188751.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1989.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2390.8 | |
| All* | Total formula weight | 193132.0 |
