3TUB
Crystal structure of SYK kinase domain with 1-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-3-((1R,2S)-2-phenylcyclopropyl)urea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein kinase SYK | polymer | 293 | 34052.1 | 1 | UniProt (P43405) Pfam (PF07714) In PDB | Homo sapiens (human) | Spleen tyrosine kinase |
| 2 | A | 1-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-3-[(1R,2S)-2-phenylcyclopropyl]urea | non-polymer | 456.5 | 1 | Chemie (FPU) | |||
| 3 | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34052.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 456.5 | |
| All* | Total formula weight | 34508.6 |
