3TTZ
Crystal structure of a topoisomerase ATPase inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA gyrase subunit B | polymer | 198 | 22545.2 | 2 | UniProt (P0A0K8) Pfam (PF02518) In PDB | Staphylococcus aureus | |
| 2 | A, B | 2-[(3S,4R)-4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-fluoropiperidin-1-yl]-1,3-thiazole-5-carboxylic acid | non-polymer | 421.3 | 2 | Chemie (07N) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
A, B: 14 - 104 (UniProt: P0A0K8)
A, B: 128 - 233 (UniProt: P0A0K8)
| PDB | External Database | Details |
|---|---|---|
| Met 13 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45090.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 964.1 | |
| All* | Total formula weight | 46054.5 |
