3TS9
Crystal Structure of the MDA5 Helicase Insert Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon-induced helicase C domain-containing protein 1 | polymer | 138 | 16453.8 | 1 | UniProt (Q8R5F7) Pfam (PF18119) | Mus musculus (mouse) | MDA-5, Melanoma differentiation-associated protein 5, Helicase with 2 CARD domains, Helicard, Interferon induced with helicase C domain protein |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 4 - 104 (UniProt: Q8R5F7)
A: 105 - 138 (UniProt: Q8R5F7)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| His 2 | - | expression tag |
| Met 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16453.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 16742.0 |
