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3TPO

Crystal structure of D192A/E396A mutant of mouse importin alpha2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AImportin subunit alpha-2polymer52957885.71UniProt (P52293)
Pfam (PF01749)
Pfam (PF00514)
Pfam (PF16186)
In PDB
Mus musculus (mouse)Importin alpha P1, Karyopherin subunit alpha-2, Pendulin, Pore targeting complex 58 kDa subunit, PTAC58, RAG cohort protein 1, SRP1-alpha
2waterwater18.0308Chemie (HOH)
Sequence modifications
A: 1 - 529 (UniProt: P52293)
PDBExternal DatabaseDetails
Ala 192Asp 192engineered mutation
Ala 396Glu 396engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight57885.7
All*Total formula weight57885.7
*Water molecules are not included.

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PDB entries from 2024-07-31

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