3TOQ
Acylphosphatase with mesophilic surface and thermophilic core
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Acylphosphatase-1 | polymer | 99 | 11183.8 | 1 | UniProt (P07311) Pfam (PF00708) | Homo sapiens (human) | Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1 |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: P07311)
| PDB | External Database | Details |
|---|---|---|
| Ala 10 | Val 10 | engineered mutation |
| Leu 12 | Tyr 12 | engineered mutation |
| Met 27 | Thr 27 | engineered mutation |
| Ala 31 | Gly 31 | engineered mutation |
| Val 36 | Leu 36 | engineered mutation |
| Ala 50 | Gly 50 | engineered mutation |
| Leu 62 | Met 62 | engineered mutation |
| Ala 66 | Leu 66 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11183.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 11278.7 |
