3TO0

Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Iodotyrosine deiodinase 1	polymer	259	29923.3	2	UniProt (Q9DCX8) Pfam (PF00881)	Mus musculus (mouse)	IYD-1
2	C, G (A, B)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
3	D, H (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E, F (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	I, J (A, B)	water	water		18.0	50	Chemie (HOH)

Sequence modifications

A, B: 34 - 285 (UniProt: Q9DCX8)

PDB	External Database	Details
Met 33	-	initiating methionine
Ala 217	Cys 217	engineered mutation
Ala 239	Cys 239	engineered mutation
His 286	-	expression tag
His 287	-	expression tag
His 288	-	expression tag
His 289	-	expression tag
His 290	-	expression tag
His 291	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59846.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1220.7
All*	Total formula weight	61067.3

*Water molecules are not included.