3TO0
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE FMN A 301 |
| Chain | Residue |
| A | HOH7 |
| A | THR235 |
| A | ARG275 |
| B | PRO123 |
| B | SER124 |
| B | GLY125 |
| B | SER212 |
| B | ACT302 |
| A | HOH20 |
| A | ARG96 |
| A | ARG97 |
| A | SER98 |
| A | ARG100 |
| A | VAL232 |
| A | THR233 |
| A | THR234 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 303 |
| Chain | Residue |
| A | HOH17 |
| A | SER103 |
| A | SER104 |
| A | ARG266 |
| B | THR284 |
| B | VAL285 |
| B | HIS286 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 302 |
| Chain | Residue |
| A | GLY125 |
| A | ALA126 |
| B | FMN301 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 302 |
| Chain | Residue |
| A | FMN301 |
| B | ALA126 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE FMN B 301 |
| Chain | Residue |
| A | PRO123 |
| A | SER124 |
| A | GLY125 |
| A | SER212 |
| A | ACT302 |
| B | ARG96 |
| B | ARG97 |
| B | SER98 |
| B | ARG100 |
| B | VAL232 |
| B | THR233 |
| B | THR234 |
| B | THR235 |
| B | ARG275 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 303 |
| Chain | Residue |
| A | THR284 |
| A | VAL285 |
| A | HIS286 |
| B | HOH14 |
| B | SER103 |
| B | SER104 |
| B | ARG266 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19436071, ECO:0000269|PubMed:22238141, ECO:0007744|PDB:3GB5, ECO:0007744|PDB:3GFD, ECO:0007744|PDB:3GH8, ECO:0007744|PDB:3TNZ, ECO:0007744|PDB:3TO0 |
| Chain | Residue | Details |
| A | ARG96 | |
| A | SER124 | |
| A | THR233 | |
| A | ARG275 | |
| B | ARG96 | |
| B | SER124 | |
| B | THR233 | |
| B | ARG275 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3GFD, ECO:0007744|PDB:3TNZ |
| Chain | Residue | Details |
| A | ALA126 | |
| B | ALA126 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19436071, ECO:0000269|PubMed:22238141, ECO:0007744|PDB:3GFD, ECO:0007744|PDB:3TNZ |
| Chain | Residue | Details |
| A | GLU153 | |
| A | TYR157 | |
| A | LYS178 | |
| B | GLU153 | |
| B | TYR157 | |
| B | LYS178 |
