3TNW
Structure of CDK2/cyclin A in complex with CAN508
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cyclin-dependent kinase 2 | polymer | 300 | 34200.6 | 2 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 2, p33 protein kinase |
| 2 | B, D (B, D) | Cyclin-A2 | polymer | 262 | 30018.6 | 2 | UniProt (P30274) Pfam (PF00134) Pfam (PF02984) | Bos taurus (bovine) | Cyclin-A |
| 3 | E, F (A, C) | 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL | non-polymer | 218.2 | 2 | Chemie (F18) | |||
| 4 | G, H (D) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 912 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 128438.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 482.4 | |
| All* | Total formula weight | 128920.9 |
